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Platelet-Derived Growth Factor (PDGF)

Summary

Platelet-Derived Growth Factor (PDGF) is a naturally occurring protein in your body that plays a vital role in tissue repair and skin rejuvenation. It works by stimulating stem cells, encouraging new collagen and elastin production, and promoting the formation of healthy blood vessels — all essential for smoother, firmer, more youthful skin.

 

In aesthetics, PDGF is often harnessed through PRP (Platelet Rich Plasma) or advanced topicals like Airessence Pure PDGF+, a pharmaceutical-grade, lab-engineered form of PDGF-BB that is bioidentical to your body’s own. Airessence delivers up to 300,000 times more potency than PRP, with a clean four-ingredient formula (PDGF-BB, hyaluronic acid, sodium acetate, and water) that ensures consistency, safety, and no need for a blood draw. Clinically proven and used in over 5 million treatments worldwide, it accelerates healing, reduces downtime, and enhances treatment outcomes.

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When applied post-procedure, PDGF helps patients experience:

  •  Reduced redness and downtime

  • Faster skin recovery

  • Improved elasticity and firmness

  • Smoother texture and fewer fine lines

  • Enhanced overall treatment results

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Because it is derived from the body’s natural healing mechanisms, PDGF-BB is safe, biocompatible, and highly effective for anyone looking to optimize their skin treatments and achieve stronger, healthier, more radiant skin.

PDGF FAQs

  • Unlike older approaches that rely on the variability of your blood or simple topical serums, PDGF-BB delivers a targeted, science-backed formulation of one of the body’s most powerful healing proteins. It represents the next evolution in regenerative skincare—providing predictable, effective, and long-lasting results.

  • PRP relies on drawing your blood, spinning it, and reapplying it to the skin. The results can vary greatly depending on your age, hydration, and even how the blood is processed that day. PDGF-BB delivers a pure, highly concentrated formulation of the exact growth factor responsible for stimulating repair. This means more consistent results, faster healing, and enhanced rejuvenation compared to PRP.

  • These treatments create controlled micro-injuries to stimulate renewal. PDGF-BB supercharges the body’s natural healing response by delivering growth factors directly into the skin. The result is reduced redness, faster recovery, and healthier skin in the days following your procedure.

  • Many patients notice improved radiance and hydration within days. Over the following weeks, collagen remodeling leads to smoother texture, better elasticity, and fewer fine lines. With a series of treatments, results compound for stronger, healthier skin that continues to improve over time.

  • Yes. By accelerating healing and stimulating collagen, PDGF-BB helps the skin recover more efficiently and hold onto results from treatments like microneedling, RF, laser, or peels. Think of it as amplifying and extending the benefits of the procedures you’re already investing in.

  •  By stimulating new collagen and supporting skin cell turnover, PDGF-BB helps soften the appearance of acne scars, fine lines, and textural irregularities. It also promotes healthier, more even-toned skin when used alongside resurfacing procedures.

  • Absolutely. PDGF-BB works at the skin level, improving quality and texture, while injectables address volume and muscle movement. When combined, the results are more comprehensive and natural-looking.

  • Most healthy adults are candidates for PDGF-BB. It is safe for all skin types and tones, making it an excellent option for patients seeking faster recovery, improved skin quality, and enhanced outcomes from other procedures

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