PRF + EZ Gel
Summary
EZ Gel is an advanced regenerative injectable derived entirely from your own blood. It contains both platelet-rich fibrin (PRF) and concentrated albumin, which are processed to form a gel-like consistency. The treatment is designed to gradually restore volume and improve skin quality through natural collagen stimulation and tissue regeneration.
How is EZ Gel different from PRF or PRP?
While PRP (platelet-rich plasma) and PRF (platelet-rich fibrin) are both concentrated blood products used to stimulate healing and collagen production, EZ Gel differs in its formulation and delivery. PRF is a liquid and stays in the treatment area only briefly before being absorbed. EZ Gel combines PRF with heat-treated albumin to create a denser, gel-like matrix that offers longer-lasting volume and a slower release of growth factors. This allows it to function more like a bio-stimulatory filler with regenerative benefits.
PRF + EZ Gel FAQ
EZ Gel works by combining two components from your blood—PRF and albumin. The PRF delivers a high concentration of growth factors, cytokines, and white blood cells that promote healing and stimulate collagen and elastin production. The albumin component is heat-treated to form a gel, which provides immediate volume while acting as a natural scaffold for the PRF to release regenerative signals over time. This dual mechanism supports both immediate and long-term improvements in skin tone, texture, and volume.
EZ Gel is not a traditional hyaluronic acid (HA) filler. It is a biostimulatory treatment that uses your own biologic material to restore volume and improve tissue quality. While it does offer some temporary volume enhancement, its primary mechanism is regenerative—stimulating your body to produce its own collagen and elastin over time. It is often used as a natural alternative to fillers in patients seeking gradual, subtle restoration without synthetic products.
EZ Gel is 100% autologous, meaning it is made entirely from your own blood. No synthetic materials, additives, or anticoagulants are used in the preparation process. This significantly reduces the risk of allergic reactions or adverse responses, making it a safe option for patients seeking natural, biocompatible treatment.
EZ Gel can be injected in areas where both volume loss and skin quality improvement are desired. Common treatment areas include:
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Under the eyes (for hollowness and discoloration)
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Temples
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Midface (cheeks)
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Jawline
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Marionette lines
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Nasolabial folds
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Chin
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Neck or décolleté (for skin texture improvement)
Because EZ Gel is autologous and regenerative rather than a structural filler, it is especially well-suited for delicate or thin-skinned areas where traditional fillers may pose a higher risk of irregularity or poor integration.
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Most patients benefit from a series of 2 to 3 treatments, spaced approximately 6 to 8 weeks apart. The exact number depends on the degree of volume loss, skin condition, and desired outcome. Maintenance sessions may be recommended once or twice a year to support ongoing collagen production.
Some subtle volume enhancement may be visible immediately due to the gel consistency of the albumin. However, true regenerative results—such as improved skin quality, collagen stimulation, and tissue remodeling—develop gradually over the course of 4 to 12 weeks following each session, as your body responds to the bioactive signals from the PRF.
To minimize bruising, bleeding, and complications, it is advised to avoid the following for at least 3–5 days before your appointment:
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Blood-thinning medications and supplements such as aspirin, ibuprofen, fish oil, turmeric, vitamin E, and gingko biloba (unless medically necessary—always check with your prescribing provider).
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Alcohol consumption
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Smoking (as it impairs healing)
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Active illness or infection
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Dental procedures or vaccinations within 2 weeks before or after treatment
Also, arrive well-hydrated and avoid makeup on the day of treatment. If you’re prone to cold sores and treating near the mouth, pre-treatment antiviral medication may be recommended.
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